Has its potential been fully exploited?

Has the measles-mumps-rubella vaccine been fully exonerated?

Neo-oogenesis: Has its existence been proven?

It was long believed that mammals are born with a fixed number of primordial follicles, each of which encloses an oocyte arrested at the diplotene step of meiotic prophase. Arising at or after birth, small numbers of primordial follicles become activated each day and enter a folliculogenic growth phase during which follicles either degenerate by atresia or complete maturation, resulting in ovul...

Acute pulmonary thromboembolism: has its evolution been redefined?

Natural History Statistics Older statistics estimate that in the United States, acute pulmonary thromboembolism afflicts 500 000 to 600 000 persons annually and is either a primary or secondary cause of death in 150 000 to 200 000 of these individuals.1,2 Extrapolation of a population-based study from data accumulated in 1985 through 1986 in Worcester, Mass, suggests that each year there are '1...

Acupuncture for major depressive disorder: has its efficacy been disproved?

Has acromegaly been diagnosed earlier?

PURPOSE We investigated whether acromegaly has been diagnosed earlier at the Niigata Medical and Dental University Hospital. METHODS Patients with acromegaly (n = 81) who underwent their first transsphenoidal surgery from 2006 to 2015 were reviewed. Two groups were compared: those who underwent surgery between 2006 and 2010 (n = 35) and those who underwent surgery between 2011 and 2015 (n = 4...